Museum of the Human Inventions
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MHI 056 · Exhibition

Vaccination

1796

Documented date

Berkeley, Gloucestershire, England

Associated with

Edward Jenner
English country doctor who tested and published the method
Benjamin Jesty
Dorset farmer who inoculated his family with cowpox in 1774
Lady Mary Wortley Montagu
Brought the practice of variolation to Britain from Constantinople in 1721

Plate 056

1796

Berkeley, Gloucestershire, England

No photograph is shown for this exhibition. The museum displays an image only where it can show the object honestly.

About this date

Edward Jenner tested cowpox material on James Phipps in May 1796. Benjamin Jesty had done something similar in 1774, and variolation was practised much earlier.

About credit

Rural people already believed cowpox protected against smallpox, and variolation was used in Asia, Africa and the Middle East before Europe. Jenner’s contribution was to test and publish it.

Chapter I

The world before

Life before Vaccination

Smallpox killed roughly three in ten of those who caught it and left many survivors scarred or blind.

The human achievement

How it came about

Jenner took matter from a cowpox sore on a dairymaid and scratched it into the arm of a boy. Later he showed that the boy resisted smallpox. He published his results in 1798. The word “vaccine” comes from vacca, Latin for cow.

Understanding the invention

How it works

Vaccination, explained in two steps.

Step 01 of 02

Training the body

A mild infection teaches the immune system to recognise a similar threat.

IV

The transformation

What changed for humanity

  1. Public health

    Mass vaccination controlled epidemics.

  2. Medicine

    Established the principle used for many later vaccines.

Vaccination led to the eradication of smallpox, declared in 1980. It is the only human disease eradicated so far.

Before and after

Life before and after Vaccination

Before

Fear of a deadly, disfiguring disease.

After

Immunity through a scratch on the arm.

On larger screens, drag the divider (or use the arrow keys) to give more room to the world before or after.

VI

Its legacy

What came after

MHI 056

Vaccination

  • In this museum

    Pasteurisation and germ theory

    Pasteur extended the vaccine idea to rabies and anthrax.

  • Beyond the collection

    Modern vaccines

    Polio, measles and COVID-19 vaccines build on it.

VII

Human stories

The people and the moments

The last natural case

The last natural case of smallpox was in Somalia in 1977. The World Health Organization declared it eradicated in 1980 after a global campaign.

Where accounts differ, this museum follows the documented record and says so.

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