The last natural case
The last natural case of smallpox was in Somalia in 1977. The World Health Organization declared it eradicated in 1980 after a global campaign.
MHI 056 · Exhibition
1796
Documented dateBerkeley, Gloucestershire, England
Plate 056
1796
Berkeley, Gloucestershire, England
Edward Jenner tested cowpox material on James Phipps in May 1796. Benjamin Jesty had done something similar in 1774, and variolation was practised much earlier.
Rural people already believed cowpox protected against smallpox, and variolation was used in Asia, Africa and the Middle East before Europe. Jenner’s contribution was to test and publish it.
The world before
Smallpox killed roughly three in ten of those who caught it and left many survivors scarred or blind.
The human achievement
Jenner took matter from a cowpox sore on a dairymaid and scratched it into the arm of a boy. Later he showed that the boy resisted smallpox. He published his results in 1798. The word “vaccine” comes from vacca, Latin for cow.
Understanding the invention
Vaccination, explained in two steps.
Step 01 of 02
A mild infection teaches the immune system to recognise a similar threat.
IV
The transformation
Mass vaccination controlled epidemics.
Established the principle used for many later vaccines.
Vaccination led to the eradication of smallpox, declared in 1980. It is the only human disease eradicated so far.
Before and after
Before
Fear of a deadly, disfiguring disease.
After
Immunity through a scratch on the arm.
On larger screens, drag the divider (or use the arrow keys) to give more room to the world before or after.
VI
Its legacy
MHI 056
Vaccination
In this museum
Pasteurisation and germ theoryPasteur extended the vaccine idea to rabies and anthrax.
Beyond the collection
Modern vaccines
Polio, measles and COVID-19 vaccines build on it.
Human stories
The last natural case of smallpox was in Somalia in 1977. The World Health Organization declared it eradicated in 1980 after a global campaign.
Where accounts differ, this museum follows the documented record and says so.
Next in the museum
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